Hantavirus cluster linked to cruise ship travel, Multi-country
- Pays / zones concernés
- Multi-country
- Premier avis
- 2026-05-04
- Dernier avis
- 2026-05-13
- Nombre d’avis
- 3
Résumé officiel (texte original)
This is the third Disease Outbreak News report on the hantavirus cluster, following the notification to the World Health Organization (WHO) on 2 May 2026 of severe respiratory illness cases aboard MV Hondius, a cruise ship. Since the last DON was published on 8 May, two additional confirmed cases were reported from France and Spain. In addition, there is one inconclusive result for a case in the United States of America. All were passengers on the ship. As of 13 May, a total of 11 cases, including three deaths, have been reported (case fatality ratio 27%). Eight cases were laboratory-confirmed for Andes virus (ANDV) infection, two are probable, and one case remains inconclusive and undergoing further testing. Through the International Health Regulations (2005) (IHR) channels, National IHR Focal Points (NFPs) have all been informed and are supporting international contact tracing efforts. WHO has assessed the risk posed by this event to the global population as low and will continue to monitor the epidemiological situation and update the risk assessment as needed.
Évaluation du risque par l’OMS (texte original)
WHO currently assesses the public health risk for those who were onboard the cruise ship as moderate, and at the Global level as low for the following reasons:
Andes virus has demonstrated limited human-to-human transmission in previous outbreaks, typically occurring among close contacts and within household settings, generally requiring prolonged close exposure. Transmission can be contained through early detection, isolation of cases, clinical management, and contact management. However, the ship environment presented an increased risk due to close living quarters, shared indoor spaces, prolonged exposure, and frequent interpersonal interactions, all of which likely facilitated transmission.The HCPS with hantaviruses in the Americas, including Andes can have a high case fatality ratio, reaching 40-50%, particularly among elderly individuals and those with co-morbidities. The average age of passengers on board the ship was 65 years old.Investigations on the travel history and potential exposures of the first case in the Southern Cone subregion of the Americas are ongoing and suggest possible exposure to rodents during bird watching activities. Viral sequencing analyses are also ongoing and will compare the ANDV strain associated with this outbreak with strains circulating in Argentina and Chile, where the disease is enzootic. The preliminary sequencing analysis for the cases indicates a high degree of genetic similarity—showing no more than one single nucleotide polymorphisms (SNP) difference per individual—strongly indicates that the outbreak likely arose from a single zoonotic spillover event, or from a very small number of closely related spillover events.[1]Additional cases may occur among individuals exposed before implementation of containment measures. However, the current response, including quarantine for those who have left the ship and rapid isolation of any new suspect cases and the monitoring of contacts, is expected to limit the risk of further spread.As there is no specific antiviral treatment for HPS, suspected cases require prompt transfer to an adequately equipped emergency department or intensive care unit, where available, for close monitoring and supportive management to improve chances of recovery. Consequently, for remote areas, rapid transfer to a mainland healthcare facility is required, which may be challenging under the current conditions.For the general public, including people not exposed on board the ship or through close contact with a confirmed case, the overall probability of infection remains low. Current evidence indicates that transmission occurs through close and prolonged contact, and can be effectively limited through early detection, isolation of cases, and contact tracing.
More detailed epidemiological, clinical and laboratory investigations are required to inform further iterations of this risk assessment.
Historique des avis
- · 2026-DON601
Hantavirus cluster linked to cruise ship travel, Multi-country
Résumé officiel (texte original)
This is the third Disease Outbreak News report on the hantavirus cluster, following the notification to the World Health Organization (WHO) on 2 May 2026 of severe respiratory illness cases aboard MV Hondius, a cruise ship. Since the last DON was published on 8 May, two additional confirmed cases were reported from France and Spain. In addition, there is one inconclusive result for a case in the United States of America. All were passengers on the ship. As of 13 May, a total of 11 cases, including three deaths, have been reported (case fatality ratio 27%). Eight cases were laboratory-confirmed for Andes virus (ANDV) infection, two are probable, and one case remains inconclusive and undergoing further testing. Through the International Health Regulations (2005) (IHR) channels, National IHR Focal Points (NFPs) have all been informed and are supporting international contact tracing efforts. WHO has assessed the risk posed by this event to the global population as low and will continue to monitor the epidemiological situation and update the risk assessment as needed.
- · 2026-DON600
Hantavirus cluster linked to cruise ship travel, Multi-country
Résumé officiel (texte original)
On 2 May 2026, a cluster of passengers with severe respiratory illness aboard a cruise ship was reported to the World Health Organization (WHO). At that time, according to the ship operator, 147 passengers and crew were onboard, and 34 passengers and crew had previously disembarked. Since the last Disease Outbreak News published on 4 May, three of the suspected cases were confirmed, and one additional confirmed case was reported. As of 8 May, a total of eight cases, including three deaths (case fatality ratio 38%), have been reported. Six cases have been laboratory-confirmed as hantavirus infections, with all identified as Andes virus (ANDV). Through the International Health Regulations (2005) (IHR) channel, National IHR Focal Points (NFPs) have all been informed and are supporting international contact tracing. WHO assesses the risk to the global population posed by this event as low and will continue to monitor the epidemiological situation and update the risk assessment. The risk for passengers and crew on the ship is considered moderate.
- · 2026-DON599
Hantavirus cluster linked to cruise ship travel, Multi-country
Résumé officiel (texte original)
On 2 May 2026, a cluster of passengers with severe respiratory illness aboard a cruise ship was reported to the World Health Organization. The ship is carrying 147 passengers and crew. As of 4 May 2026, seven cases (two laboratory confirmed cases of hantavirus and five suspected cases) have been identified, including three deaths, one critically ill patient and three individuals reporting mild symptoms. Illness onset occurred between 6 and 28 April 2026 and was characterized by fever, gastrointestinal symptoms, rapid progression to pneumonia, acute respiratory distress syndrome and shock. Further investigations are ongoing. The outbreak is being managed through coordinated international response, and includes in-depth investigations, case isolation and care, medical evacuation and laboratory investigations.
Human hantavirus infection is primarily acquired through contact with the urine, faeces, or saliva of infected rodents. It is a rare but severe disease that can be deadly. Although uncommon, limited human to human transmission has been reported in previous outbreaks of Andes virus (a specific species of hantavirus).
WHO currently assesses the risk to the global population from this event as low and will continue to monitor the epidemiological situation and update the risk assessment.
