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DIABETES & KIDNEYSDiabetes damages kidneys — butnow there are drugs that help1Diabetes is the leading cause of new dialysis in the USand many other countries; long-term high glucose damagesthe kidney filters, usually silently at first.2If you have diabetes, guidelines advise checking eGFRand urine albumin (UACR) at least once a year to catchdamage early.3Glucose targets are individual: an HbA1c target anywherefrom <6.5% to <8.0% may be appropriate, depending on age,hypoglycaemia risk and other conditions.4SGLT2 inhibitors: recommended for type 2 diabetes withCKD and eGFR ≥20 — they slow kidney decline and protectthe heart.5Metformin can be used at eGFR ≥30 (reduce the dose at30–44); not advised below 30. Medicines must be adjustedas kidney function changes — ask your doctor to reviewregularly.With diabetes, ask at your next visit: "Have I had a UACR this year? Am I acandidate for an SGLT2 inhibitor?"BBeyond CKDbeyondckd.com/it/cards/diabetes-and-kidneysSources: KDIGO 2022 Clinical Practice Guideline for Diabetes Management in CKD · USRDS…Compiled from public clinical guidelines · General education, not individual medical advice
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Diabetes & kidneys

Diabetes damages kidneys — but now there are drugs that help

Diabetes is the leading cause of dialysis in many countries — but the last few years brought medicines that protect the kidneys.

  1. 1Diabetes is the leading cause of new dialysis in the US and many other countries; long-term high glucose damages the kidney filters, usually silently at first.
  2. 2If you have diabetes, guidelines advise checking eGFR and urine albumin (UACR) at least once a year to catch damage early.
  3. 3Glucose targets are individual: an HbA1c target anywhere from <6.5% to <8.0% may be appropriate, depending on age, hypoglycaemia risk and other conditions.
  4. 4SGLT2 inhibitors: recommended for type 2 diabetes with CKD and eGFR ≥20 — they slow kidney decline and protect the heart.
  5. 5Metformin can be used at eGFR ≥30 (reduce the dose at 30–44); not advised below 30. Medicines must be adjusted as kidney function changes — ask your doctor to review regularly.

With diabetes, ask at your next visit: "Have I had a UACR this year? Am I a candidate for an SGLT2 inhibitor?"

Didascalia (pronta da incollare)

Diabetes is the leading cause of dialysis in many countries — but the last few years brought medicines that protect the kidneys.

1. Diabetes is the leading cause of new dialysis in the US and many other countries; long-term high glucose damages the kidney filters, usually silently at first.
2. If you have diabetes, guidelines advise checking eGFR and urine albumin (UACR) at least once a year to catch damage early.
3. Glucose targets are individual: an HbA1c target anywhere from <6.5% to <8.0% may be appropriate, depending on age, hypoglycaemia risk and other conditions.
4. SGLT2 inhibitors: recommended for type 2 diabetes with CKD and eGFR ≥20 — they slow kidney decline and protect the heart.
5. Metformin can be used at eGFR ≥30 (reduce the dose at 30–44); not advised below 30. Medicines must be adjusted as kidney function changes — ask your doctor to review regularly.

With diabetes, ask at your next visit: "Have I had a UACR this year? Am I a candidate for an SGLT2 inhibitor?"

Fonti: KDIGO 2022 Clinical Practice Guideline for Diabetes Management in CKD — Kidney Int 2022;102(5S):S1–S127; USRDS 2023 Annual Data Report — ESRD: Incidence, Prevalence, Patient Characteristics
Verificato il: 2026-10-16

Schede e script sono informazione sanitaria generale tratta da linee guida cliniche pubbliche. Non sono consigli medici individuali e non sostituiscono la valutazione di medico, farmacista o dietista. Mantieni fonti e questa nota quando condividi; questa pagina contiene la versione più recente.
https://beyondckd.com/it/cards/diabetes-and-kidneys
Script video breve 60 s

Inquadrature e voce fuori campo. Verticale 9:16; sottotitoli nel terzo inferiore. Ogni frase rimanda alle fonti a sinistra.

sSchermoVoce
0–5Glucose meter + kidney iconWhy does diabetes damage the kidneys — and is there anything that can stop it now?
5–15Bar chart: #1 cause of dialysis "diabetes"In the US and many countries, diabetes is the leading cause of new dialysis. High glucose damages the kidney filters for years, almost without symptoms.
15–25Calendar tick "eGFR + UACR"That is why guidelines advise people with diabetes to check eGFR and urine albumin, UACR, at least once a year.
25–35HbA1c scale 6.5–8.0Glucose targets are individual. An HbA1c below 6.5 or below 8 may both be right, depending on age, hypoglycaemia risk and other illnesses.
35–47Pill "SGLT2i" + kidney & heart shieldHere is the key: SGLT2 inhibitors. For type 2 diabetes with kidney disease and eGFR 20 or above, guidelines recommend them — they slow kidney decline and protect the heart.
47–55Metformin + "eGFR ≥30"Metformin is fine at eGFR 30 and above, reduced at 30 to 44, not advised below 30. When kidney function changes, medicines must change too.
55–60Site logo + URL + QRAsk at your next visit: am I a candidate for an SGLT2 inhibitor? More at Beyond CKD.

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Verificato il: 2026-10-16