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HEART & VESSELSFish-oil capsules vs eatingfish1VITAL (NEJM 2019): 1 g/day fish oil vs placebo,5.3 years2Major cardiovascular events: no significantdifference (HR 0.92, 0.80–1.06)3Secondary analyses: fewer heart attacks, but theprimary endpoint was negative4People eating little fish (<1.5 servings/week)may have benefited more5Eating fish itself tracks with lower risk — it’smore than omega-36High-dose prescription fish oil (4 g) is aseparate question with separate trialsTwo servings of fish a week has steadier evidence than capsules.Kidney patients: fish contains phosphorus — ask your dietitian.BBeyond CKDbeyondckd.com/de/cards/fish-oil-pills-vs-fishSources: Manson JE et al. VITAL: marine n-3 fatty acids · 2026-10-17Compiled from public clinical guidelines · General education, not individual medical advice
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Heart & vessels

Fish-oil capsules vs eating fish

A daily fish-oil pill to prevent heart disease? The 25,871-person VITAL trial disappointed.

  1. 1VITAL (NEJM 2019): 1 g/day fish oil vs placebo, 5.3 years
  2. 2Major cardiovascular events: no significant difference (HR 0.92, 0.80–1.06)
  3. 3Secondary analyses: fewer heart attacks, but the primary endpoint was negative
  4. 4People eating little fish (<1.5 servings/week) may have benefited more
  5. 5Eating fish itself tracks with lower risk — it’s more than omega-3
  6. 6High-dose prescription fish oil (4 g) is a separate question with separate trials

Two servings of fish a week has steadier evidence than capsules. Kidney patients: fish contains phosphorus — ask your dietitian.

Bildunterschrift (direkt einfügbar)

A daily fish-oil pill to prevent heart disease? The 25,871-person VITAL trial disappointed.

1. VITAL (NEJM 2019): 1 g/day fish oil vs placebo, 5.3 years
2. Major cardiovascular events: no significant difference (HR 0.92, 0.80–1.06)
3. Secondary analyses: fewer heart attacks, but the primary endpoint was negative
4. People eating little fish (<1.5 servings/week) may have benefited more
5. Eating fish itself tracks with lower risk — it’s more than omega-3
6. High-dose prescription fish oil (4 g) is a separate question with separate trials

Two servings of fish a week has steadier evidence than capsules. Kidney patients: fish contains phosphorus — ask your dietitian.

Quellen: Manson JE et al. VITAL: marine n-3 fatty acids — N Engl J Med 2019
Geprüft am: 2026-10-17

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https://beyondckd.com/de/cards/fish-oil-pills-vs-fish
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Sek.BildVoice-over
0–5Golden capsuleA fish-oil pill a day keeps the cardiologist away?
5–25VITAL numbersVITAL: 25,871 people, over five years — no significant difference in major cardiovascular events.
25–45Fish vs capsule on a scaleLow fish eaters may benefit a little; but two servings of fish a week has steadier evidence.
45–60Phosphorus labelKidney patients: fish has phosphorus. Check portions and types with a dietitian.

Quellen (jeder Punkt auf der Karte lässt sich zuordnen)

Geprüft am: 2026-10-17