Anti-rejection Medication Timing Converter

Anti-rejection Medication Timing Converter

Pick your drug, enter the last dose and both time zones, and see what local time the next dose is due; add flight times to check whether a dose falls mid-flight.

The interval never changes. Next dose = time you actually took the last dose + standard interval (e.g. 12 h for tacrolimus). Time zones change the wall clock, not your body's clock.

Shift slowly. If you want a more convenient local time, move by 1–2 hours per day — not 8 hours at once.

Ask your team first. This tool only converts time. Any change to dose or schedule should be confirmed with your transplant team; trough levels are drawn before the dose.

Defaults to the usual interval for the drug (e.g. tacrolimus every 12 h). If your prescription differs, type the number directly (e.g. 8, 12, 24).

Flight times (optional)

Marks any dose times that fall during the flight.

Gradually shift to a convenient local time (optional)

e.g. 9:00 / 21:00 in Taiwan → 9:00 / 21:00 New York time.

Fill in the left side and press "Calculate next dose".

How this is calculated

  1. Dosing intervals come from FDA / EMA labels (every 12 h or every 24 h) and transplant-centre guidance (UHN, Duke, BC Transplant): same time every day, interval unchanged.
  2. All times are converted to UTC, the interval is added, and the result is displayed in the destination zone; daylight-saving is handled by the browser's Intl time-zone database.
  3. Gradual shifting follows travel-medicine convention — 1–2 hours per day to minimise level swings; each gap is constrained to standard interval ± shift.
  4. Missed-dose rules are from labels: immediate-release tacrolimus / cyclosporine can be taken if <6 h late; extended-release tacrolimus within 14–15 h; mycophenolate skipped if the next dose is <4 h away; never double.

Sources: DailyMed labels; UHN Post-Transplant Manual (2023); Duke Kidney Transplant Program; BC Transplant Patient Guide (2024); Gale Health "Medications Across Time Zones".

The content of this article is personal reflection and experience sharing only, and is not medical advice. For any questions about your health, illness or physical care, please seek help through professional medical channels and consult your physician.