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Medication safety
Pain relief with kidney disease: avoid NSAIDs
Headache — grab any painkiller? With kidney disease, check which kind first.
- 1Common NSAIDs: ibuprofen, diclofenac, naproxen, mefenamic acid, celecoxib, and aspirin at pain-relief doses. Many combination cold remedies contain them too.
- 2KDIGO guidance: avoid NSAIDs when eGFR is below 30; no prolonged use when eGFR is below 60.
- 3The "triple whammy": an NSAID plus an ACE inhibitor/ARB plus a diuretic clearly raises the risk of acute kidney injury.
- 4Risk is higher when you are ill and dehydrated (vomiting, diarrhoea, fever) — ask your doctor which medicines to pause on sick days.
- 5For occasional pain, acetaminophen (paracetamol) within the recommended dose is usually the safer choice — but still ask first; patches and gels are absorbed too.
Before buying any painkiller, ask the pharmacist one question: "I have kidney disease — is this safe for me?"
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Headache — grab any painkiller? With kidney disease, check which kind first. 1. Common NSAIDs: ibuprofen, diclofenac, naproxen, mefenamic acid, celecoxib, and aspirin at pain-relief doses. Many combination cold remedies contain them too. 2. KDIGO guidance: avoid NSAIDs when eGFR is below 30; no prolonged use when eGFR is below 60. 3. The "triple whammy": an NSAID plus an ACE inhibitor/ARB plus a diuretic clearly raises the risk of acute kidney injury. 4. Risk is higher when you are ill and dehydrated (vomiting, diarrhoea, fever) — ask your doctor which medicines to pause on sick days. 5. For occasional pain, acetaminophen (paracetamol) within the recommended dose is usually the safer choice — but still ask first; patches and gels are absorbed too. Before buying any painkiller, ask the pharmacist one question: "I have kidney disease — is this safe for me?" 출처(카드의 각 항목과 대응): KDIGO 2024 CKD Guideline — Ch. 4 (medication safety, NSAIDs, sick-day guidance); KDIGO 2012 CKD Guideline — Rec. 4.4 (NSAIDs: avoid at GFR <30; no prolonged use at GFR <60); Lapi F et al. NSAIDs + diuretics + ACEi/ARB and acute kidney injury — BMJ 2013;346:e8525; NKF — Pain Medicines (Analgesics) and the kidneys 확인일: 2026-10-16 카드와 대본은 공개 임상 가이드라인에 근거한 일반 건강 교육 정보이며 개인 의료 조언이 아니고 의사·약사·영양사의 평가를 대신하지 않습니다. 공유 시 출처와 이 안내를 유지해 주세요. 최신판은 이 페이지가 기준입니다. https://beyondckd.com/ko/cards/painkillers-and-kidneys
60초 숏폼 영상 대본
장면과 내레이션. 세로 9:16, 자막은 하단 1/3에. 각 내레이션은 왼쪽 출처와 대응.
| 초 | 화면 | 내레이션 |
|---|---|---|
| 0–5 | Hand reaching for painkillers on a pharmacy shelf | Headache, grab a painkiller? If you have kidney disease, wait a second. |
| 5–17 | Drug list: ibuprofen, diclofenac, naproxen… | Many common painkillers are NSAIDs — ibuprofen, diclofenac, naproxen — and plenty of cold remedies contain them. They reduce blood flow to the kidneys. |
| 17–28 | "eGFR <30 avoid | <60 no long-term use" | KDIGO guidelines say: avoid NSAIDs if eGFR is below 30, and no long-term use below 60. |
| 28–40 | Three pills colliding: NSAID + ACEi/ARB + diuretic → ⚠️ | Watch out for the triple whammy: an NSAID plus a blood-pressure drug like an ACE inhibitor or ARB, plus a diuretic — acute kidney injury risk goes up clearly. |
| 40–50 | Sick person icon, "ask your doctor" | The risk is higher when you are ill and dehydrated. Vomiting, diarrhoea, fever — ask your doctor which medicines to pause. |
| 50–60 | Pharmacy counter speech bubble + site logo + QR | For occasional pain, acetaminophen within the recommended dose is usually safer. But always ask: I have kidney disease — is this OK for me? More at Beyond CKD. |
출처(카드의 각 항목과 대응)
- KDIGO 2024 CKD Guideline — Ch. 4 (medication safety, NSAIDs, sick-day guidance)
- KDIGO 2012 CKD Guideline — Rec. 4.4 (NSAIDs: avoid at GFR <30; no prolonged use at GFR <60)
- Lapi F et al. NSAIDs + diuretics + ACEi/ARB and acute kidney injury — BMJ 2013;346:e8525
- NKF — Pain Medicines (Analgesics) and the kidneys
확인일: 2026-10-16