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Brain, nerves & mind
Stroke: 4.5 hours and 24 hours
“Nothing can be done, sleep on it” is a leading avoidable cause of stroke disability. Two time windows decide everything.
- 1IV thrombolysis: within 3 h OR 1.75, 3–4.5 h OR 1.26, beyond 4.5 h no significant benefit (6,756-patient meta-analysis)
- 2Benefit holds regardless of age or severity — including over 80
- 3Thrombectomy (large-vessel occlusion): independence 46% vs 26.5%; treat 2.6 to reduce disability in 1
- 4Selected patients can be treated up to 24 h — but only imaging in hospital can tell
- 5Every minute of delay costs about 1.9 million neurons
- 6Don’t drive yourself, don’t take pills first, don’t wait for family
Kidney patients especially: emergency imaging tells ischaemic from bleed; thrombolysis and thrombectomy are not contraindicated in CKD.
نص المنشور (جاهز للّصق)
“Nothing can be done, sleep on it” is a leading avoidable cause of stroke disability. Two time windows decide everything. 1. IV thrombolysis: within 3 h OR 1.75, 3–4.5 h OR 1.26, beyond 4.5 h no significant benefit (6,756-patient meta-analysis) 2. Benefit holds regardless of age or severity — including over 80 3. Thrombectomy (large-vessel occlusion): independence 46% vs 26.5%; treat 2.6 to reduce disability in 1 4. Selected patients can be treated up to 24 h — but only imaging in hospital can tell 5. Every minute of delay costs about 1.9 million neurons 6. Don’t drive yourself, don’t take pills first, don’t wait for family Kidney patients especially: emergency imaging tells ischaemic from bleed; thrombolysis and thrombectomy are not contraindicated in CKD. المصادر: Emberson J et al. Alteplase IPD meta-analysis — Lancet 2014; Goyal M et al. HERMES thrombectomy IPD meta-analysis — Lancet 2016 تاريخ التحقّق: 2026-10-17 تُعدّ البطاقات والنصوص مواد تثقيف صحي عام مُنظَّمة بالاستناد إلى إرشادات سريرية علنية، وليست نصيحة طبية فردية، ولا تغني عن تقييم الطبيب أو الصيدلاني أو اختصاصي التغذية. يُرجى الإبقاء على المصادر وهذا البيان عند المشاركة؛ وأي تحديث للمحتوى يكون اعتمادُه على هذه الصفحة. https://beyondckd.com/ar/cards/stroke-time-is-brain
نص مقطع فيديو قصير مدته 60 ثانية
تقسيم المشاهد والتعليق الصوتي. عمودي 9:16، يُفضَّل وضع الترجمة في الثلث السفلي من الشاشة؛ كل جملة في التعليق الصوتي تقابلها المصادر في العمود الأيسر.
| ثانية | المشهد | التعليق الصوتي |
|---|---|---|
| 0–5 | Stopwatch | A stroke — watch overnight and see? |
| 5–25 | 4.5-hour hourglass | Nine trials, 6,756 people: clot-buster within 3 hours raises the odds of no disability by 75%; after 4.5 hours the benefit is gone. |
| 25–45 | 46% vs 26.5% | Thrombectomy for large-vessel occlusion: independence rises from 26.5% to 46% — fewer than 3 treated to help 1. |
| 45–60 | Emergency number | Every minute costs 1.9 million neurons. Note the time, call emergency services. Kidney patients too — these treatments are not off-limits. |
المصادر (كل نقطة على البطاقة يمكن إسنادها لمصدر)
- Emberson J et al. Alteplase IPD meta-analysis — Lancet 2014
- Goyal M et al. HERMES thrombectomy IPD meta-analysis — Lancet 2016
تاريخ التحقّق: 2026-10-17